Thermo Fisher Scientific MTA1 Monoclonal Antibody (1C3)
MTA1 단백질을 타겟으로 하는 Thermo Fisher Scientific의 Mouse Monoclonal Antibody(1C3). Western blot 및 ELISA에 적합하며, Human 시료에 반응. 비결합형 액상 형태로 제공되며, -20°C에서 보관 권장.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1C3 |
| Immunogen | MTA1 (NP_004680, 601 a.a. – approximately 700 a.a) partial recombinant protein with GST tag. MW of GST tag alone is 26 kDa. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Storage Buffer | Ascites |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MPSRGLANHG QTRHMGPSRN LLLNGKSYPT KVRLIRGGSL PPVKRRRMNW IDAPDDVFYM ATEETRKIRK LLSSSETKRA ARRPYKPIAL RQSQALPPRP
Target Information
This gene encodes a protein identified in a screen for genes expressed in metastatic cells, particularly mammary adenocarcinoma cell lines. Expression of this gene correlates with metastatic potential in certain carcinomas, though it is also expressed in many normal tissues. The exact role in metastasis is unclear. Initially thought to be the 70 kDa component of the NuRD complex, it is now believed to be a similar but distinct protein. Both share domains involved in DNA binding, dimerization, and methylation-related functions. The protein likely regulates transcription through chromatin remodeling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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