Thermo Fisher Scientific MTA1 Monoclonal Antibody (1F12)
MTA1 단백질을 인식하는 Mouse monoclonal antibody (Clone 1F12). Western blot 및 ELISA에 적합하며 Human 시료에 반응. 비결합(Unconjugated) 형태의 액상 제품으로 -20°C 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1F12 |
| Immunogen | MTA1 (NP_004680, 601 a.a. – approximately 700 a.a.) partial recombinant protein with GST tag. MW of the GST tag alone is 26 kDa. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Storage Buffer | Ascites |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein:
MPSRGLANHG QTRHMGPSRN LLLNGKSYPT KVRLIRGGSL PPVKRRRMNW IDAPDDVFYM ATEETRKIRK LLSSSETKRA ARRPYKPIAL RQSQALPPRP
Target Information
This gene encodes a protein identified in a screen for genes expressed in metastatic cells, particularly mammary adenocarcinoma cell lines. Expression correlates with metastatic potential in multiple carcinoma types but is also found in many normal tissues. Its role in metastasis remains unclear.
Initially thought to be the 70 kDa component of the NuRD complex, it is now believed to be a distinct but related protein. Both share similar domains, including DNA-binding, dimerization, and methylation-related regions, suggesting involvement in transcriptional regulation via chromatin remodeling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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