Thermo Fisher Scientific Phospho-DAXX (Ser739) Polyclonal Antibody
Human DAXX 단백질의 Ser739 인산화 부위를 인식하는 Rabbit Polyclonal Antibody. Western blot에 적합하며 Human, Mouse, Rat 시료에서 반응. 액상 형태, 1 mg/mL 농도, PBS/glycerol buffer에 보관. 연구용 한정 제품.
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Applications
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide sequence derived from Human DAXX around phosphorylation site of serine 739 (L-S-D-S(p)-D) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2692163 |
Product Specific Information
Predicted to react with Mouse and Rat samples.
Target Information
This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with various proteins such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1.
In the nucleus, it functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by sequestration into promyelocytic leukemia nuclear bodies or nucleoli.
This protein also associates with centromeres in G2 phase. In the cytoplasm, it may regulate apoptosis. The subcellular localization and function are modulated by post-translational modifications, including sumoylation, phosphorylation, and polyubiquitination.
Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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