Thermo Fisher Scientific Phospho-Fumarase (Thr236) Polyclonal Antibody
인간, 마우스, 랫트 시료에서 반응하는 Thr236 인산화 부위 특이적 폴리클로날 항체. Western blot에 적합하며 고순도 친화 크로마토그래피 정제 제품. 액상 형태로 제공되며 안정적인 PBS/glycerol 버퍼에 보관. 연구용으로만 사용 가능.
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Thermo Fisher Scientific Phospho-Fumarase (Thr236) Polyclonal Antibody
Applications
- Western Blot (WB): 1:500–1:1,000 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide sequence derived from Human Fumarase around phosphorylation site of threonine 236 (T-H-T(p)-Q-D) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2692178 |
Product Specific Information
Predicted to react with Mouse and Rat samples.
Target Information
The protein encoded by this gene is an enzymatic component of the tricarboxylic acid (Krebs) cycle and catalyzes the formation of L-malate from fumarate. It exists in both cytosolic and mitochondrial forms, differing by the translation start site. The mitochondrial form is generated by removal of an N-terminal extension. The enzyme functions as a homotetramer and belongs to the thermostable class II fumarases. Mutations in this gene can cause fumarase deficiency, leading to progressive encephalopathy.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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