Thermo Fisher Scientific Phospho-PGCA (Ser529, Thr532, Ser542) Polyclonal Antibody, Biotin
Phospho-PGCA (Ser529, Thr532, Ser542)에 특이적인 Biotin 결합 폴리클로날 항체로, WB, ELISA, IP 등 다양한 응용에 사용 가능. Rabbit에서 유래한 IgG 항체로, 고순도의 Affinity chromatography 정제. -20°C 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat, Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide taken within amino acid region 500–550 on human Atrial natriuretic peptide receptor 1 protein |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Guanylyl cyclases catalyze the production of cGMP from GTP and are classified as soluble and membrane forms. The membrane guanylyl cyclases (A–F) form a family of cell-surface receptors with similar structures: an extracellular ligand-binding domain, a single membrane-spanning domain, and an intracellular region containing a protein kinase-like domain and a cyclase catalytic domain.
GC-A and GC-B act as receptors for natriuretic peptides, also known as atrial natriuretic peptide receptor A and type B. NPR1 is a membrane-bound guanylate cyclase that serves as the receptor for both atrial and brain natriuretic peptides (BNP).
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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