Thermo Fisher Scientific Phospho-PGCA (Ser529, Thr532, Ser542) Polyclonal Antibody
Human, Mouse, Rat에 반응하는 Rabbit Polyclonal Antibody로, PGCA의 인산화 부위를 인식합니다. WB, ELISA, IP에 사용 가능하며, Affinity chromatography로 정제되었습니다. 액상 형태로 -20°C에서 보관합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 500–550 on human Atrial natriuretic peptide receptor 1 (NPR1) protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 0.5% BSA, 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Guanylyl cyclases catalyze the production of cGMP from GTP and exist as soluble and membrane forms. The membrane guanylyl cyclases (A–F) are cell-surface receptors with an extracellular ligand-binding domain, a single membrane-spanning domain, and an intracellular region containing a protein kinase-like and a cyclase catalytic domain.
GC-A and GC-B serve as receptors for natriuretic peptides, also known as atrial natriuretic peptide receptor A and type B. NPR1 encodes a membrane-bound guanylyl cyclase that functions as the receptor for both atrial and brain natriuretic peptides.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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