Thermo Fisher Scientific MCP-1 Monoclonal Antibody (ECE.2)
Mouse MCP-1 (CCL2) 단백질을 인식하는 Rat IgG1 단클론 항체. Western blot 및 동결 절편 면역조직화학(IHC-F) 검증 완료. 단백질 G 정제, PBS/BSA buffer, 4°C 보관. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:50
Immunohistochemistry (Frozen) (IHC-F)
- Tested Dilution: 1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rat / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | ECE.2 |
| Immunogen | Synthetic peptide corresponding to residues 102–130 of mouse MCP-1 (CCL2, UniProt ID: P10148-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 100 µg/mL |
| Purification | Protein G |
| Storage Buffer | PBS with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
| RRID | AB_3091203 |
Additional Formats
Product Specific Information
The monoclonal antibody ECE.2 recognizes mouse monocyte chemoattractant protein 1 (MCP-1).
Target Information
This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene belongs to the CXC subfamily of cytokines, characterized by two cysteines separated by a single amino acid. MCP-1 exhibits chemotactic activity for monocytes and basophils, but not for neutrophils or eosinophils. It is implicated in diseases with monocytic infiltrates such as psoriasis, rheumatoid arthritis, and atherosclerosis. MCP-1 binds to chemokine receptors CCR2 and CCR4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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