Thermo Fisher Scientific IL-2 Monoclonal Antibody (MQ1-17H12), PE-Cyanine7, eBioscience
인간 IL-2를 인식하는 비중화성 단클론 항체로, PE-Cyanine7 형광체가 결합되어 있습니다. 유세포분석(Flow Cytometry)에 최적화되어 있으며, 5 µL/test로 사용 가능합니다. 빛에 민감하므로 어두운 곳에 4°C에서 보관합니다.
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2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific IL-2 Monoclonal Antibody (MQ1-17H12), PE-Cyanine7, eBioscience
Applications and Tested Dilution
- Application: Flow Cytometry (Flow)
- Tested Dilution: 5 µL (0.125 µg)/test
- Publications: View 21 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human, Rhesus monkey |
| Host / Isotype | Rat / IgG2a, kappa |
| Recommended Isotype Control | Rat IgG2a kappa Isotype Control (eBR2a), PE-Cyanine7, eBioscience™ |
| Class | Monoclonal |
| Type | Antibody |
| Clone | MQ1-17H12 |
| Conjugate | PE-Cyanine7 |
| Excitation / Emission Max | 569 / 780 nm |
| Form | Liquid |
| Concentration | 5 µL/Test |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 0.2% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2573517 |
Available Formats
- Unconjugated
- Alexa Fluor 532
- APC
- Brilliant UV 395
- Brilliant UV 615
- Brilliant UV 737
- Brilliant Violet 421
- Brilliant Violet 480
- eFluor 450
- FITC
- PE
- PE-eFluor 610
- PerCP-eFluor 710
- Request custom conjugation
Product Specific Information
The MQ1-17H12 antibody reacts with human interleukin-2 (IL-2), a 17 kDa T cell growth factor and major immunoregulatory cytokine. This antibody is non-neutralizing.
- Applications Reported: Intracellular staining followed by flow cytometric analysis.
- Applications Tested: Pre-titrated and tested by intracellular staining and flow cytometric analysis of normal human peripheral blood cells.
- Use at 5 µL (0.125 µg) per test (100 µL final volume).
- Suitable for 10⁵–10⁸ cells/test.
Light Sensitivity:
This tandem dye is sensitive to photo-induced oxidation. Protect from light.
Fixation:
Samples can be stored in:
- IC Fixation Buffer (Product # 00-822-49)
- 1-step Fix/Lyse Solution (Product # 00-5333-54)
Store up to 3 days in the dark at 4°C.
Excitation / Emission: 488–561 nm / 775 nm
Laser Compatibility: Blue, Green, Yellow-Green Laser
Filtration: 0.2 µm post-manufacturing filtered
Target Information
Interleukin-2 (IL-2) is an immunomodulatory cytokine essential for proliferation of activated T cells and differentiation of B cells, NK cells, monocytes, and macrophages. IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric complex whose gamma chain is shared with IL-4 and IL-7. Monoallelic expression of IL-2 in mature thymocytes represents a unique regulatory mechanism. Disruption of the IL-2 gene in mice results in colitis-like disease, highlighting its crucial role in immune regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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