Thermo Fisher Scientific RXRG/NR2B3 (Transcription Factor) Monoclonal Antibody (PCRP-RXRG-5G6)
RXRG/NR2B3 전사인자에 특이적인 Thermo Fisher Scientific의 단클론 항체로, 인간 시료에 반응하며 Flow, ELISA, IP, Peptide Array 등 다양한 응용에 적합. 단백질 A/G로 정제된 액상 형태이며, 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Flow Cytometry (Flow) | 1–2 µg/10⁶ cells |
| ELISA (ELISA) | Assay-dependent |
| Immunoprecipitation (IP) | 1–2 µg/100–500 µg total protein |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | PCRP-RXRG-5G6 |
| Immunogen | Recombinant full-length human RXRG protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Predicted to react in Mouse, Rat, Chick.
Target Information
Retinoic Acid (RA), the active metabolite of vitamin A, regulates the transition of proliferating precursor cells (such as carcinoma and neuronal precursors) to postmitotic differentiated cells (Joshi et al., 2005).
The Retinoid X Receptors (RXRs) family—RXR alpha, beta, and gamma—preferentially bind 9-cis-RA and regulate gene transcription by forming heterodimers with RA receptors.
RAs may have therapeutic potential in cervical cancer (Abu et al., 2005) and play key roles in neuronal development. Evidence suggests that retinoid signaling regulates synaptic plasticity and learning and memory behaviors (Lane and Bailey, 2005).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일 정보: 6258-MSM2-P1ABX_RXRG_P48443-1_House_mouse.svg, 6258-MSM2-P1ABX_RXRG_P48443-1_House_mouse_PDP.jpeg)
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