Thermo Fisher Scientific Synaptophysin Polyclonal Antibody
Synaptophysin 단백질을 인식하는 Sheep 유래 Polyclonal 항체로, Western blot 및 IHC에 사용 가능. 인간 시료 반응성 검증. 동결건조 형태로 제공되며, 장기 보관 시 -20°C 권장. 신경세포 및 신경내분비 종양 연구용으로 적합.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 10–50 µg/mL | - |
| Immunohistochemistry (IHC) | 10–50 µg/mL | - |
| Miscellaneous PubMed (Misc) | - | View 3 publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Sheep / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from human Synaptophysin (SYP) conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 500 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: Synaptophysin.
Target Information
Synaptophysin is a calcium-binding integral membrane glycoprotein found in presynaptic vesicles of nearly all neurons. It contains four transmembrane domains and forms a complex with dynamin at high calcium concentrations, suggesting a role in synaptic vesicle endocytosis. Synaptophysin is involved in short- and long-term synaptic plasticity regulation and is widely used as a marker for nerve terminals and neuroendocrine tumor differentiation. Mutations in the gene may result in mental retardation, X-linked 96.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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