Thermo Fisher Scientific Synaptophysin Polyclonal Antibody
Synaptophysin 단백질을 인식하는 Sheep 유래 Polyclonal 항체로, WB 및 IHC에 적합합니다. 신경 말단 및 신경내분비 종양 마커 연구에 활용됩니다. 동결 건조 형태로 제공되며, 장기 보관 시 -20°C에서 안정적으로 보관 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 2 publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Sheep / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from internal region of mouse Synaptophysin conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: Synaptophysin.
Target Information
Synaptophysin is a calcium-binding integral membrane glycoprotein found in presynaptic vesicles of nearly all neurons. It contains four transmembrane domains and forms a complex with dynamin at high calcium concentrations, suggesting a role in synaptic vesicle endocytosis.
It also contributes to the regulation of short- and long-term synaptic plasticity and serves as a widely used marker for nerve terminals and neuroendocrine tumor differentiation.
Mutations in the Synaptophysin gene have been associated with X-linked mental retardation (MRX96).
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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