Thermo Fisher Scientific SYNM Monoclonal Antibody (OTI3D10), TrueMAB
SYNM 단백질을 인식하는 마우스 단클론 항체로, Western blot 및 IHC(P)에서 검증됨. 인간 시료에 반응하며, 동결건조 형태로 제공. PBS 완충액 기반, 방부제 무첨가. 연구용으로 세포골격 단백질 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3D10 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 329–580 of human SYNM produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional round of desalting (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
SYNM (Synemin) is a type-VI intermediate filament (IF) protein that plays a key cytoskeletal role in muscle cells.
It forms heteropolymeric IFs with desmin and/or vimentin, and interacts with cytoskeletal proteins such as alpha-dystrobrevin, dystrophin, talin-1, utrophin, and vinculin.
These interactions link IFs to adherens-type junctions, including costameres, neuromuscular junctions, and myotendinous junctions within striated muscle cells.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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