Thermo Fisher Scientific SYNM Monoclonal Antibody (OTI5G1), TrueMAB
Human SYNM 단백질(aa 329-580)에 특이적인 Mouse IgG1 단클론 항체로, IHC(P)에서 1:150 희석으로 사용 가능. 무보존제, 동결건조 형태이며 PBS/trehalose 버퍼에 저장. 근육세포 세포골격 연구에 적합.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): Tested dilution 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5G1 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 329–580 of human SYNM produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).
Target Information
Type-VI intermediate filament (IF) protein that plays a crucial cytoskeletal role within muscle cells.
Forms heteropolymeric IFs with desmin and/or vimentin, and interacts with cytoskeletal proteins such as alpha-dystrobrevin, dystrophin, talin-1, utrophin, and vinculin, linking these IFs to adherens-type junctions (costameres, neuromuscular junctions, myotendinous junctions) in striated muscle cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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