Thermo Fisher Scientific CPA1 (Carboxypeptidase A1) Monoclonal Antibody (OTI4F1), TrueMAB
Human CPA1 단백질을 인식하는 Mouse monoclonal antibody (Clone OTI4F1). Western blot과 IHC(P)에서 검증됨. Affinity chromatography로 정제된 Lyophilized 형태로 제공되며, PBS buffer에 8% trehalose 포함. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4F1 |
| Immunogen | Recombinant protein expressed in E. coli corresponding to amino acids 1–419 of human CPA1 |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
CPA1 (Carboxypeptidase A1) is a 419 amino acid secreted monomeric protein highly expressed in pancreatic tissue. It functions as a pancreatic exopeptidase using zinc as a cofactor to catalyze the release of C-terminal amino acids from proteins, playing a key role in protein digestion and degradation.
CPA1 may also be involved in zymogen inhibition, regulating enzyme activation pathways. Abnormal CPA1 levels are associated with pancreatic cancer, suggesting potential roles in tumor progression or suppression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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