Thermo Fisher Scientific WDR35 Polyclonal Antibody
Rabbit polyclonal antibody against human WDR35 protein. Validated for IHC (Paraffin) applications. Antigen affinity purified and supplied in PBS with 40% glycerol. For research use only. Recommended storage at 4°C short term or -20°C long term.
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Applications and Tested Dilution
- Immunohistochemistry (Paraffin) (IHC (P)): 1:20–1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human WDR35. Recombinant protein control fragment (Product # RP-99642) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2649570 |
Product Specific Information
Immunogen sequence:
SLPNVGLIQK YSLNCRAYQL SLNCNSSRLA IIDISGVLTF FDLDARVTDS TGQQVVGELL KLERRDVWDM KWAKDNPDLF AMMEKTRMYV FRNLDPEEPI QTSGY
- Highest antigen sequence identity to orthologs:
- Mouse: 93%
- Rat: 93%
Target Information
WD40 repeats are a common structural module in eukaryotic proteins. Proteins containing WD40 domains have diverse functions including signal transduction, cell cycle regulation, RNA splicing, and transcription.
WDR35 (also known as CED2) is associated with Sensenbrenner syndrome / cranioectodermal dysplasia (CED), an autosomal-recessive disorder characterized by craniosynostosis and skeletal abnormalities.
WDR35 localizes to cilia and centrosomes during embryogenesis. Cells lacking this gene fail to produce cilia, and mutations can lead to short-rib polydactyly syndromes due to abnormal ciliogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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