Thermo Fisher Scientific Humicade Chimeric Recombinant Mouse Monoclonal Antibody (CDP 571 (Humicade))

Applications

Tested Dilution

Publications

ELISA (ELISA)

Assay-dependent

-

Neutralization (Neu)

Assay-dependent

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1, kappa

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

CDP 571 (Humicade)

Immunogen

Human TNF-alpha.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS

Contains

0.02% ProClin 300

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

Product Specific Information

The antibody binds to human TNF-alpha with a Kd of 0.087 nM.

Target Information

The structure of Humicade is a monoclonal antibody that is highly similar to the reference medicine, Humira (adalimumab). It is composed of human immunoglobulin G1 (IgG1) antibodies that are produced using recombinant DNA technology. The function of Humicade is to treat certain autoimmune conditions by blocking the action of tumor necrosis factor-alpha (TNF-alpha), a protein that contributes to inflammation. The structure of Humicade allows it to specifically target TNF-alpha and block its activity, reducing inflammation and alleviating symptoms in certain autoimmune conditions.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.