Thermo Fisher Scientific Humicade Chimeric Recombinant Human Monoclonal Antibody (CDP 571 (Humicade))
인간 TNF-α에 결합하는 재조합 인간 단일클론 항체로 염증성 질환 연구용에 적합함. HEK293 세포에서 발현된 IgG4 형태이며 Protein A로 정제됨. ELISA, IHC, 중화시험 등 다양한 응용 가능. 연구용으로만 사용.
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Thermo Fisher Scientific Humicade Chimeric Recombinant Human Monoclonal Antibody (CDP 571, Humicade)
Applications and Tested Dilution
| Application | Tested Dilution | Notes |
|---|---|---|
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 5 µg/mL | |
| ELISA | Assay-dependent | |
| Neutralization (Neu) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Human / IgG4, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | CDP 571 (Humicade) |
| Immunogen | Human TNF-alpha |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
Product Specific Information
The antibody binds to human TNF-alpha with a Kd of 0.087 nM.
Target Information
Humicade is a chimeric recombinant human monoclonal antibody structurally similar to the reference medicine Humira (adalimumab).
It consists of human IgG1 antibodies produced via recombinant DNA technology.
Its primary function is to block tumor necrosis factor-alpha (TNF-alpha), a key mediator of inflammation, thereby reducing inflammatory responses in autoimmune conditions.
This product is intended for research use only and not for diagnostic or therapeutic applications.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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