Thermo Fisher Scientific Muromonab Chimeric Recombinant Mouse Monoclonal Antibody (OKT-3 (muromonab))
인간 CD3 복합체의 epsilon 서브유닛을 인식하는 재조합 마우스 단클론 항체입니다. Flow Cytometry 등 다양한 면역분석에 사용됩니다. Protein A로 정제되었으며, 1 mg/mL 농도의 액상 형태입니다. 연구용으로만 사용 가능합니다.
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Applications
- Flow Cytometry (Flow): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | OKT-3 (muromonab) |
| Immunogen | Human peripheral E+ cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
Product Specific Information
Epitope on the epsilon-subunit within the human CD3 complex.
Target Information
Muromonab is a murine monoclonal antibody specific to CD3 T-cell lymphocyte antigens. It is a purified mouse monoclonal antibody directed against the CD3 (T3) receptor on the surface of human T-cells (T-lymphocytes), cultured using the murine ascites method.
Muromonab is 93% monomeric IgG2a and binds to the T-cell surface glycoprotein CD3 epsilon chain. It kills CD3-positive cells by inducing Fc-mediated apoptosis, antibody-mediated cytotoxicity, and complement-dependent cytotoxicity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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