
Thermo Fisher Scientific HSPBAP1 Polyclonal Antibody
HSPBAP1 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot에 적합하며 인간과 마우스 시료 반응. 항원 친화 크로마토그래피로 정제되어 순도 95% 이상. 세포 스트레스 반응 및 발암 연구용으로 유용.
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Applications
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues in Human HSPBAP1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2719564 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. The purity is greater than 95% as determined by SDS-PAGE.
Target Information
HSPBAP1 (HSPB-associated protein 1), also known as PASS1, is a 488-amino acid cytoplasmic protein containing one JMJC (Jumonji C) domain and shares 80% identity with its rat homolog. It is widely expressed, with highest levels in ovary, thymus, and pancreas, and is implicated in cellular stress response regulation. The JMJC domain suggests a role in chromatin remodeling. Genetic defects or translocations in HSPBAP1 are associated with renal cell carcinoma 1 (RCC1), indicating its potential involvement in carcinogenesis. Three isoforms exist due to alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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