Thermo Fisher Scientific BFAR Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:2,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:1,000-1:5,000

-

Immunoprecipitation (IP)

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A recombinant protein corresponding to amino acids 1-139 of human BAR. Human BAR is 450 amino acid protein; GenBank no. NP_057645.1. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:BFAR,uniProtId:Q9NZS9-1,ncbiNodeId:9606,antigenRange:1-139,antigenLength:450,antigenImageFileName:PA5-72900_BFAR_Q9NZS9-1_Rabbit.svg,antigenImageFileNamePDP:PA5-72900_BFAR_Q9NZS9-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

Conc. Not Determined

Storage buffer

whole serum

Contains

0.05% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2718754

Target Information

The bifunctional apoptosis inhibitor (BFAR) is scaffold protein that integrates signaling components of the cells apoptosis-regulatory machinery. BFAR is a multidomain protein capable of inhibiting apoptosis induced by TNF-family death receptors (extrinsic pathway) as well as mitochondria-dependent apoptosis (intrinsic pathway). Interaction of BFAR with Bcl-2 or Bcl-XL via a SAM domain may contribute to the anti-apoptotic properties of BFAR. In addition, BFAR contains a DED-like domain that is capable of suppressing apoptosis mediated at the receptor level. BFAR is also thought to be involved in the regulation of neuronal survival.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.