Thermo Fisher Scientific GRAMD4 (Transcription Factor) Monoclonal Antibody (PCRP-GRAMD4-1A10)
Human GRAMD4 단백질을 인식하는 Mouse IgG1 단일클론 항체로, ICC/IF, Flow Cytometry, Peptide Array 등 다양한 응용에 적합. 단백질 A/G로 정제된 액상 형태이며 4°C 보관. 암 연구 및 GRAMD4 관련 세포사멸 기전 연구용.
- 카탈로그번호
- 23151-MSM1-P0
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific GRAMD4 (Transcription Factor) Monoclonal Antibody (PCRP-GRAMD4-1A10)
Applications
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg / 10⁶ cells |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | PCRP-GRAMD4-1A10 |
| Immunogen | Recombinant full-length human GRAMD4 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Predicted to react in Rat.
Target Information
GRAMD4, also known as Death Inducing Protein, is a 578-amino acid multi-pass membrane protein containing one GRAM domain. It localizes to the mitochondrial membrane and its overexpression induces apoptosis via caspase-3 activation and PARP cleavage. GRAMD4 is expressed in lung tissue and primary lung squamous cell carcinoma (LSCC), and its expression is upregulated by E2F-1 after treatment with 4-hydroxytamoxifen. These characteristics suggest GRAMD4 may serve as a potential target for cancer therapy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.