Thermo Fisher Scientific E-cadherin Monoclonal Antibody (M168)
E-cadherin 단백질을 인식하는 Mouse monoclonal antibody (Clone M168). WB, IHC, ICC/IF, IP 등 다양한 응용에 적합. Human, Mouse, Rat 반응성. Protein A 정제, PBS/BSA/glycerol buffer에 보관. 암 연구 및 세포 접착 관련 연구용.
✨AI 추천 연관 상품
AI가 분석한 이 상품과 연관된 추천 상품들을 확인해보세요
연관 상품을 찾고 있습니다...
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:250 |
| Immunoprecipitation (IP) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | M168 |
| Immunogen | Mouse recombinant E-Cadherin protein containing amino acids in the cytoplasmic region. Highly conserved in human and rat E-cadherin. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.25 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with 1 mg/mL BSA, 50% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2942631 |
Product Specific Information
This E-cadherin antibody detects a 120 kDa protein in human A431 cells, and does not cross-react with VE-cadherin or N-cadherin.
Target Information
E-Cadherin (epithelial cadherin) is a classical cadherin belonging to the calcium-dependent adhesion protein superfamily. It is a cell-cell adhesion glycoprotein composed of five extracellular cadherin repeats, a transmembrane region, and a conserved cytoplasmic tail. Mutations in this gene are associated with gastric, breast, colorectal, thyroid, and ovarian cancers. Loss of E-cadherin function contributes to cancer progression by increasing proliferation, invasion, and metastasis. The ectodomain mediates bacterial adhesion, while the cytoplasmic domain is required for internalization. E-cadherin plays a key role in tissue architecture and integrity. In humans, it is encoded by the CDH1 gene on chromosome 16. Reduced or lost expression of E-cadherin in carcinomas correlates with higher invasion and metastasis potential.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
🏷️Thermo Fisher Scientific 상품 둘러보기
동일 브랜드의 다른 상품들을 확인해보세요
Thermo Fisher Scientific
Thermo Fisher Scientific CD55 Monoclonal Antibody (M033)
802,600원
Thermo Fisher Scientific
Thermo Fisher Scientific CD59 Monoclonal Antibody (M015)
802,600원
Thermo Fisher Scientific
Thermo Fisher Scientific E-cadherin Monoclonal Antibody (M168)
802,600원
Thermo Fisher Scientific
Thermo Fisher Scientific CD59 Monoclonal Antibody (M011)
802,600원
Thermo Fisher Scientific
Thermo Fisher Scientific B7-H3 (CD276) Monoclonal Antibody (M045)
802,600원
배송/결제/교환/반품 안내
배송 정보
| 기본 배송비 |
| 교환/반품 배송비 |
|
|---|---|---|---|
| 착불 배송비 |
| ||
| 교환/반품 배송비 |
| ||
결제 및 환불 안내
| 결제수단 |
|
|---|---|
| 취소 |
|
| 반품 |
|
| 환급 |
|
교환 및 반품 접수
| 교환 및 반품 접수 기한 |
|
|---|---|
| 교환 및 반품 접수가 가능한 경우 |
|
| 교환 및 반품 접수가 불가능한 경우 |
|
교환 및 반품 신청
| 교환 절차 |
|
|---|---|
| 반품 절차 |
|