Thermo Fisher Scientific NOD2 Polyclonal Antibody
Rabbit 유래의 NOD2 폴리클로날 항체로, 인간 NOD2 단백질을 인식합니다. NF-κB 조절 및 염증성 장질환 연구에 적합합니다. 액상 형태로 제공되며, 단기 4°C, 장기 -20°C 보관 권장. 연구용으로만 사용 가능합니다.
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Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human NOD2 (amino acids 635–723) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.10 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2856804 |
Product Specific Information
Immunogen sequence:
PGNSPMARLL PTMCIQASEG KDSSVAALLQ KAEPHNLQIT AAFLAGLLSR EHWGLLAECQ TSEKALLRRQ ACARWCLARS LRKHFHSIP
Target Information
NOD2 is a member of the apoptosis-regulating protein family that includes caspase recruitment domains, as well as Apaf-1 and NOD1. It contains two N-terminal CARDs, a nucleotide-binding domain (NBD), and multiple C-terminal leucine-rich repeats (LRRs). NOD2 is expressed in monocytes (whereas NOD1 is expressed in multiple tissues). NOD2 plays a role in regulating NF-kappaB, acts as an intracellular receptor for bacterial lipopolysaccharides, and contributes to inflammatory bowel disease (IBD) and Crohn’s disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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