Thermo Fisher Scientific HEXA Polyclonal Antibody
Rabbit에서 유래한 IgG 폴리클로날 항체로 인간 HEXA 단백질을 인식합니다. 액상 형태이며 비결합(Unconjugated) 상태로 제공됩니다. 4°C 단기 보관, -20°C 장기 보관 권장. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific HEXA Polyclonal Antibody
제품 사양
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Protein corresponding to Human HEXA |
| Conjugate | Unconjugated |
| Form | Liquid |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2856805 |
Product Specific Information
Immunogen sequence:
LESFYIQTLL DIVSSYGKGY VVWQEVFDNK VKIQPDTIIQ VWREDIPVNY MKELELVTKA GFRALLSAPW YLNRISYGPD WKDFYVVEPL AFE
Target Information
This gene encodes the alpha subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2 and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both subunits belong to family 20 of glycosyl hydrolases. Mutations in these genes cause accumulation of GM2 ganglioside in neurons, leading to neurodegenerative disorders termed GM2 gangliosidoses. Mutations in the alpha subunit gene result in Tay-Sachs disease (GM2-gangliosidosis type I).
주의 사항
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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