Thermo Fisher Scientific CLEC5A Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Protein corresonding to Human CLEC5A. Recombinant protein control fragment (Product #RP-108400). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CLEC5A,uniProtId:Q9NY25-1,ncbiNodeId:9606,antigenRange:56-120,antigenLength:188,antigenImageFileName:PA5-111388_CLEC5A_Q9NY25-1_Rabbit.svg,antigenImageFileNamePDP:PA5-111388_CLEC5A_Q9NY25-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2856798

Product Specific Information

Immunogen sequence: PSPNGFITTR SYGTVCPKDW EFYQARCFFL STSESSWNES RDFCKGKGST LAIVNTPEKL KFLQD

Target Information

Functions as a positive regulator of osteoclastogenesis. Cell surface receptor that signals via TYROBP. Regulates inflammatory responses. Acts as a key regulator of synovial injury and bone erosion during autoimmune joint inflammation. Critical macrophage receptor for dengue virus serotypes 1-4. The binding of dengue virus to CLEC5A triggers signaling through the phosphylation of TYROBP, this interaction does not result in viral entry, but stimulates proinflammatory cytokine release.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.