Thermo Fisher Scientific EVER2 Polyclonal Antibody
Human EVER2 단백질에 특이적인 Rabbit Polyclonal Antibody로, IHC(P)에서 1:200–1:500 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관. 연구용으로만 사용.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:200–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human EVER2. Recombinant protein control fragment (Product # RP-91030) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2856802 |
Product Specific Information
Immunogen sequence:
VQLENYPPNT EVNLTLIWCV VLKLASLGMF SVSLGQTILC IGRDKSSCES YGYNVCDYQC WENSVGEELY KLS
Target Information
Epidermodysplasia verruciformis (EV) is an autosomal recessive genodermatosis associated with a high risk of skin cancers resulting from a high susceptibility to infection by specific human papillomaviruses. Mutations in two homologous genes, EVER1 and EVER2, cause the majority of EV cases. These proteins form a complex and interact with the zinc transporter ZnT-1 in the endoplasmic reticulum. Cells lacking EVER2 accumulate higher levels of zinc in the nucleolus and nucleus compared to those with an intact EVER2 gene, indicating that one role of EVER2 is to regulate intracellular zinc distribution.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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