Thermo Fisher Scientific TIA1 Monoclonal Antibody (OTI1D7), TrueMAB
TIA1 단백질을 인식하는 Mouse monoclonal 항체로 Western blot 및 IHC(파라핀 절편)에 적합. HEK293T 세포에서 발현된 full-length human recombinant 단백질을 면역원으로 사용. 동결건조 형태로 제공되며, PBS buffer에 8% trehalose 포함. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1D7 |
| Immunogen | Full length human recombinant protein of human TIA1 produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitution: Add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
- For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Noggin is involved in numerous developmental processes such as neural tube fusion and joint formation. Organ morphogenesis is initiated by downgrowth from epithelial stem cells, regulated by signals from:
- WNT3A (stabilizes beta-catenin)
- Noggin (BMP inhibitor)
Mutations in Noggin are associated with proximal symphalangism (SYM1) and multiple synostoses syndrome (SYNS1), characterized by multiple joint fusions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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