
Thermo Fisher Scientific TIA1 Monoclonal Antibody (OTI1C3), TrueMAB
Human TIA1 단백질을 인식하는 Mouse IgG2b 단클론 항체로 Western blot에 최적화됨. 동결건조 형태로 제공되며, 재구성 후 약 1 mg/mL 농도 유지. 보존제 무첨가 PBS 버퍼에 8% 트레할로스 포함. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1C3 |
| Immunogen | Full length human recombinant protein of human TIA1 produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Noggin is involved in numerous developmental processes such as neural tube fusion and joint formation. Organ morphogenesis is initiated by epithelial stem cell downgrowth, regulated by WNT3A-mediated β-catenin stabilization and Noggin, a bone morphogenetic protein inhibitor.
Mutations in Noggin have been linked to proximal symphalangism (SYM1) and multiple synostoses syndrome (SYNS1), characterized by multiple joint fusion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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