Thermo Fisher Scientific N-WASP Polyclonal Antibody
Thermo Fisher Scientific의 N-WASP Polyclonal Antibody는 인간, 생쥐, 랫트에 반응하는 다클론 항체로 Western blot, IHC, ICC/IF 등에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS 버퍼(40% 글리세롤)로 보관됩니다. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | - |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 | - |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL | - |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human N-WASP. Recombinant protein control fragment (Product #RP-88621) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2644914 |
Product Specific Information
Immunogen sequence:
DHQVPTTAGN KAALLDQIRE GAQLKKVEQN SRPVSCSGRD ALLDQIRQGI QLKSVADGQE STPPTPAPTS GIVGALMEVM QKRS
Highest antigen sequence identity to the following orthologs:
- Mouse: 95%
- Rat: 95%
Target Information
The Wiskott-Aldrich syndrome (WAS) family of proteins share similar domain structures and are involved in transduction of signals from receptors on the cell surface to the actin cytoskeleton. These proteins are regulated by multiple stimuli and interact with various other proteins. Studies show that they associate with the small GTPase Cdc42, which regulates actin filament formation, and the cytoskeletal organizing complex Arp2/3. The WASL gene product, homologous to WAS protein, is ubiquitously expressed and most highly in neural tissues, binding directly to Cdc42 and inducing formation of long actin microspikes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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