Thermo Fisher Scientific ETV4 Polyclonal Antibody
Rabbit에서 유래한 ETV4 폴리클로날 항체로 인간 ETV4 단백질을 인식합니다. 비결합형 액상 형태이며 0.05 mg/mL 농도입니다. 단기 4°C, 장기 -20°C 보관이 권장됩니다. 연구용으로만 사용 가능합니다.
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Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ETV4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2641139 |
Product Specific Information
Immunogen sequence:
YLGEHSSVFQ QPLDICHSFT SQGGGREPLP APYQHQLSEP CPPYPQQSFK QEYHDPLYEQ AGQPAVDQGG VNGHRYPGAG VVIKQEQTDF AYDSDVTGCA SMYLHTEGFS GPSPGDGAMG YGYEKPLRPF PDDVCVVPEK FEGDIKQEGV
Highest antigen sequence identity to the following orthologs:
- Mouse: 91%
- Rat: 90%
Target Information
ETV4 (E1A enhancer binding protein, E1AF) — also known as PEA3.
Several members of the Ets gene family encode sequence-specific DNA binding proteins, including mouse PU.1, mouse and human Ets-1, Drosophila E74, chicken and human Ets-2, and rat GABP-α.
These proteins recognize similar DNA motifs with a central 5'-GGAA-3' element. For example, PEA3 binds the motif 5'-AGGAAG-3' (the PEA3 motif), but not 5'-AGGAAC-3', which is recognized by PU.1.
All Ets proteins recognize the same core sequence but interact with unique flanking sequences.
PEA3 is expressed in epithelial and fibroblastic cells but not in hematopoietic cells, contrasting with other Ets family members such as Ets-1, Ets-2, and Fli-1, which are primarily expressed in hematopoietic cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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