Thermo Fisher Scientific ARMX2 Polyclonal Antibody
Human ARMX2 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P)와 ICC/IF에서 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보존. 종 특이성은 Human이며 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:50 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ARMX2. Recombinant protein control fragment (Product #RP-92150). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2638230 |
Product Specific Information
Immunogen sequence:
RDQTKKRMAK PKNRAVAGTG ARARAGLRAG FTIDLGSGFS PPTPVRAEAE DRAQDEASAL DTVGAEAVAP AASSAEAQSG AGSQAQEADG AGVGPKAESV VGAAMASAIA PPPGVTEALG AAEAPAMAGA PKVAEAPREA ETSRA
Highest antigen sequence identity to orthologs:
- Mouse: 59%
- Rat: 55%
Target Information
The armadillo (ARM) repeat family of proteins are related to the Drosophila melanogaster armadillo protein, essential for wingless signal transduction. ARM proteins are involved in processes such as cell migration, proliferation, tissue maintenance, tumorigenesis, and signal transduction.
ARMCX2 (armadillo repeat containing, X-linked 2), also known as ALEX2, is a 632 amino acid single-pass membrane protein with three ARM repeats. It is highly expressed in testis, brain, ovary, heart, colon, spleen, and prostate, and is thought to play a role in tumor suppression.
The gene encoding ARMCX2 maps to human chromosome X, which contains nearly 153 million base pairs and houses over 1,000 genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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