Thermo Fisher Scientific IRF4 Polyclonal Antibody
IRF4 단백질을 인식하는 Thermo Fisher Scientific의 Goat Polyclonal Antibody로, Human 및 Mouse 시료에 반응합니다. Western blot에 최적이며, 고순도(Ammonium sulfate precipitation)로 정제된 액상 형태입니다. 연구용으로만 사용됩니다.
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Thermo Fisher Scientific IRF4 Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 0.5–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-HISNPEDYHRSIR (aa 433–445) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933492 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:64,000.
Target Information
The IRF (interferon regulatory factor) family of transcription factors are characterized by a unique tryptophan pentad repeat DNA-binding domain. The IRFs regulate interferons in response to viral infection and control interferon-inducible genes.
IRF4 is lymphocyte-specific and negatively regulates toll-like receptor (TLR) signaling, which is central to innate and adaptive immune activation.
A chromosomal translocation involving IRF4 and the IgH locus, t(6;14)(p25;q32), may contribute to multiple myeloma. Alternatively spliced transcript variants have been identified.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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