Thermo Fisher Scientific IRF4 Polyclonal Antibody
IRF4 단백질을 인식하는 염소 유래 폴리클로날 항체로, WB, IHC, Flow Cytometry에 사용 가능. 인간 및 랫트 반응성. 액상 형태로 제공되며 0.5 mg/mL 농도. IRF4의 두 가지 isoform을 모두 인식하며 연구용으로 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–0.3 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5 µg/mL |
| Flow Cytometry (Flow) | 10 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-DPQRQRKLITAHVEP |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933493 |
Product Specific Information
- This antibody is expected to recognize both reported isoforms.
- Tested in Peptide ELISA: antibody detection limit dilution 1:16,000.
Target Information
The IRF (interferon regulatory factor) family of transcription factors are characterized by a unique tryptophan pentad repeat DNA-binding domain. IRFs regulate interferons in response to viral infection and control interferon-inducible genes.
IRF4 is lymphocyte-specific and negatively regulates toll-like receptor (TLR) signaling, which is central to innate and adaptive immune activation.
A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be associated with multiple myeloma. Alternatively spliced transcript variants have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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