Thermo Fisher Scientific NOG Polyclonal Antibody, MaxPab
Rabbit polyclonal antibody against human Noggin (NOG) protein. Validated for Western blot at 1:500–1:1,000 dilution. Affinity purified and supplied in PBS buffer without preservative. Suitable for research use in developmental and signaling studies.
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Applications
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | NOG (NP_005441.1, 1–232 a.a.) full-length human protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MERCPSLGVT LYALVVVLGL RATPAGGQHY LHIRPAPSDN LPLVDLIEHP DPIFDPKEKD LNETLLRSLL GGHYDPGFMA TSPPEDRPGG GGGAAGGAED LAELDQLLRQ RPSGAMPSEI KGLEFSEGLA QGKKQRLSKK LRRKLQMWLW SQTFCPVLYA WNDLGSRFWP RYVKVGSCFS KRSCSVPEGM VCKPSKSVHL TVLRWRCQRR GGQRCGWIPI QYPIISECKC SC
Target Information
Noggin is involved in numerous developmental processes, such as neural tube fusion and joint formation. Organ morphogenesis is initiated by downgrowth from epithelial stem cells, regulated by WNT3A (stabilizing β-catenin) and Noggin, a bone morphogenetic protein inhibitor. Mutations in Noggin are associated with proximal symphalangism (SYM1) and multiple synostoses syndrome (SYNS1), characterized by multiple joint fusions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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