Thermo Fisher Scientific PTTG1 Monoclonal Antibody (3H4)
PTTG1 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체(3H4)입니다. 인간 시료에 반응하며 ELISA에 적합합니다. PBS(pH 7.4) 용액 형태로 제공되며 방부제는 포함되지 않습니다. -20°C에서 보관하며 동결/해동을 피해야 합니다.
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Applications
- ELISA (ELISA)
Tested Dilution: 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG3, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3H4 |
| Immunogen | PTTG1 (AAI08895.1, 179 a.a. ~ 190 a.a.) partial recombinant protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
LQSPSSILST LDC
Target Information
The encoded protein is a homolog of yeast securin proteins, which prevent separins from promoting sister chromatid separation. It is an anaphase-promoting complex (APC) substrate that associates with separin until activation of the APC. The gene product has transforming activity in vitro and tumorigenic activity in vivo, and is highly expressed in various tumors. It contains two PXXP motifs required for its transforming and tumorigenic activities and stimulation of basic fibroblast growth factor expression. It also has a destruction box (D box) required for degradation by the APC. The acidic C-terminal region can act as a transactivation domain. The protein is mainly cytosolic, with partial nuclear localization.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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