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Thermo Fisher Scientific Phospho-NEDD4L (Ser479) Polyclonal Antibody
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인간 및 랫트에서 인산화된 Ser479 위치의 NEDD4L을 특이적으로 검출하는 폴리클로날 항체. Western blot에 적합하며, 1 mg/mL 농도의 액상 형태로 제공. PBS와 50% 글리세롤 버퍼에 보존되며 -20°C에서 저장. 연구용으로만 사용 가능.
- 판매단위
- pk
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마지막 업데이트 2025. 08. 02. 오후 11:15
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Thermo Fisher Scientific PA5105691 Phospho-NEDD4L (Ser479) Polyclonal Antibody 100 ul pk판매 단위 pk ·
재고 확인 필요
627,600원VAT 포함 690,360원
Thermo Fisher Scientific · Thermo Fisher Scientific Phospho-NEDD4L (Ser479) Polyclonal Antibody
Applications
- Western Blot (WB): Tested dilution 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human NEDD4L (Accession Q96PU5), corresponding to amino acid residues around phosphorylated Ser479 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2817119 |
Product Specific Information
This antibody detects endogenous levels of NEDD4L only when phosphorylated at Ser479.
Target Information
NEDD4L is an E3 ubiquitin-protein ligase that transfers ubiquitin from an E2 conjugating enzyme to target substrates. It inhibits TGF-beta signaling by promoting ubiquitination and degradation of SMAD2 and TGFR1. NEDD4L also facilitates ubiquitination and internalization of plasma membrane channels (ENaC, Nav1.2–1.8, Kv1.3, EAAT1, CLC5) and promotes degradation of SGK.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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