Thermo Fisher Scientific Factor VIII Monoclonal Antibody (9035)

Applications

Tested Dilution

Publications

Western Blot (WB)

5-10 µg/mL

-

ELISA (ELISA)

5-10 µg/mL

-

Product Specifications

Species Reactivity

Mouse

Host/Isotype

Rat

Class

Monoclonal

Type

Antibody

Clone

9035

Immunogen

Mouse Factor VIII.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

8.1 mg/mL

Purification

SDS-PAGE

Storage buffer

50% water with 50% glycerol

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2101746

Product Specific Information

MA1-43037 detects Factor VIII in mouse samples.

MA1-43037 has successfully been used in Western blot and ELISA applications.

MA1-43037 was derived from mouse factor VIII.

Target Information

This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.