Thermo Fisher Scientific CD142 Recombinant Rabbit Monoclonal Antibody (34)

Applications

Product Specifications

Product Specific Information

This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The antibody DNA sequences from immunoreactive rabbits are cloned, and individual clones are screened to select the best candidates for production.

Advantages of recombinant rabbit monoclonal antibodies:

• Better specificity and sensitivity
• Lot-to-lot consistency
• Animal origin-free formulations
• Broader immunoreactivity to diverse targets due to the larger rabbit immune repertoire

This antibody has specificity for Mouse Coagulation Factor III / Tissue Factor / CD142 / F3.

Target Information

This gene encodes coagulation factor III, a cell surface glycoprotein that enables cells to initiate blood coagulation cascades. It functions as the high-affinity receptor for coagulation factor VII. The resulting complex provides a catalytic event responsible for initiating the coagulation protease cascades by specific limited proteolysis.

Unlike other cofactors in these cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. It contains three distinct domains: extracellular, transmembrane, and cytoplasmic. Notably, congenital deficiency of this protein has not been described.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.