Thermo Fisher Scientific Prothrombin Recombinant Rabbit Monoclonal Antibody (318)
Recombinant rabbit monoclonal antibody specific for mouse Prothrombin (Coagulation Factor II/F2). Western blot validated with high specificity and consistency. Preservative-free liquid form, 1 mg/mL concentration. Suitable for research use only.
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Applications
Western Blot (WB)
- Tested dilution: 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 318 |
| Immunogen | Recombinant Mouse Coagulation Factor II/F2 Protein (Met1–Gly618) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4 °C short term; for long-term storage, store at −20 °C, avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2785524 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The antibody DNA sequences from immunoreactive rabbits are cloned, and individual clones are screened to select optimal candidates for production.
Advantages of recombinant rabbit monoclonal antibodies:
- Enhanced specificity and sensitivity
- Lot-to-lot consistency
- Animal-origin–free formulation
- Broader immunoreactivity due to larger rabbit immune repertoire
This antibody shows specificity for Mouse Coagulation Factor II/F2.
Target Information
Prothrombin (Coagulation Factor II, F2) is a precursor of thrombin, which plays a central role in the coagulation cascade leading to blood clot formation. It also contributes to maintaining vascular integrity during development and postnatal life. Mutations in F2 are associated with thrombosis and dysprothrombinemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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