Thermo Fisher Scientific TLX Monoclonal Antibody (H6510)
인간, 생쥐, 랫드 TLX 단백질을 특이적으로 인식하는 단클론 항체입니다. Western blot, IHC, ELISA, IP 등 다양한 응용에 사용 가능합니다. 비결합형 액상 형태이며, 1 mg/mL 농도로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 20 µg/mL |
| ELISA | 0.3 µg/mL |
| Immunoprecipitation (IP) | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | H6510 |
| Immunogen | Produced in BALB/c mouse ascites after inoculation with hybridoma of mouse myeloma cells (NS-1) and spleen cells derived from a BALB/c mouse immunized with Baculovirus-expressed recombinant human TLX (81-180 aa). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | Physiological saline |
| Contains | 0.1% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 1 month. For long-term storage, store at -20°C. |
| Shipping Conditions | Wet ice |
| RRID | AB_2532210 |
Product Specific Information
This antibody specifically recognizes human TLX and cross-reacts with mouse and rat TLX.
Target Information
Nuclear receptor TLX, a NR2 hepatocyte NF4-like receptor, is involved in anterior brain differentiation, retinal development, and vision. TLX regulates genes such as RAR beta2 and Pax2 during retinal development. Homozygous TLX mutant mice show reduced forebrain development and increased aggression. Deletion of the TLX locus leads to cerebral hypoplasia, blindness, and extreme aggression (fierce phenotype). TLX expression is documented in mouse brain and eye, and ESTs have been isolated from normal human brain libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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