Thermo Fisher Scientific TGFBR3 Polyclonal Antibody
TGFBR3 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC에 사용 가능. Human 시료에 반응하며 Mouse, Rat, Pig에서도 예측 반응. 항원 친화 크로마토그래피로 정제되었으며, 4°C 또는 -20°C에서 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:3,000 | - |
| Immunohistochemistry (IHC) | - | 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 88–314 of TGF beta Receptor III (Uniprot ID: Q03167) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.31 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_11153727 |
Product Specific Information
- Recommended positive control: THP-1
- Predicted reactivity: Mouse (87%), Rat (88%), Pig (89%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This locus encodes the transforming growth factor (TGF)-beta type III receptor.
The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members.
Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling.
Decreased expression of this receptor has been observed in various cancers.
Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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