Thermo Fisher Scientific SNTB2 Polyclonal Antibody
SNTB2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF에 적합하며, 인간에 반응. 고순도 항원 친화 크로마토그래피 정제, 액상 형태로 제공. 연구용으로만 사용 가능.
- 카탈로그번호
- PA521990
- 판매단위
- pk
카탈로그
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to amino acids 174–540 of SNTB2 (Uniprot ID: Q13425) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.84 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_11157671 |
Product Specific Information
- Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Raji
- Predicted reactivity: Mouse (96%), Rat (96%), Bovine (98%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Syntrophins are structurally related proteins located at the neuromuscular synapse and play an important role in dystrophin-associated protein (DAP) complex formation.
Three distinct syntrophin isoforms have been identified: alpha 1, beta 1, and beta 2.
Each protein contains a PDZ domain, a syntrophin-unique domain (SU), and three pleckstrin homology domains (PH1a, PH1b, and PH2).
The PDZ domain mediates binding of syntrophin to nNOS and the DAP complex, localizing the nicotinic acetylcholine receptor to the cytoskeleton via the (S/T)XV C terminus.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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