Thermo Fisher Scientific DUSP3 Polyclonal Antibody
DUSP3 단백질을 인식하는 Thermo Fisher Scientific의 rabbit polyclonal antibody로, WB 및 IP에 적합. 인간, 마우스, 원숭이, 랫트 반응성. 항원 친화 크로마토그래피로 정제된 액상 시약이며, 교차반응 없음. 연구용으로만 사용.
- 카탈로그번호
- PA517625
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Immunoprecipitation (IP)
- Tested Dilution: 1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to human DUSP3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10982411 |
Product Specific Information
- It is not recommended to aliquot this antibody.
- This antibody is not cross-reactive with other dual-specific phosphatases.
Target Information
Protein tyrosine phosphatases (PTPs) are enzymes that remove phosphate groups from phosphorylated tyrosine residues on proteins. Together with tyrosine kinases, PTPs regulate phosphorylation of key signaling molecules such as the MAP kinase family.
Dual specificity phosphatases (DSPs) are a subclass of PTPs that selectively dephosphorylate phosphothreonine and phosphotyrosine residues. The prototypical DSP is the VH1 gene in vaccinia virus expressed in late-stage infection.
VHR’s shallow active site allows hydrolysis of phosphorylated serine, threonine, or tyrosine residues, while deeper active sites in PTPs restrict substrate specificity to phosphotyrosine only.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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