
Thermo Fisher Scientific SMAD2/SMAD3 Polyclonal Antibody
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SMAD2/SMAD3 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 Immunoprecipitation에 적합. TGFβ/BMP 신호전달 연구용. 고순도 항원 친화 크로마토그래피 정제. 연구용으로만 사용.
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Thermo Fisher Scientific SMAD2/SMAD3 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunoprecipitation (IP) | 1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues in the amino-terminal region of Smad2/3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 41 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10977529 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
Smad proteins, the mammalian homologs of the Drosophila mothers against decapentaplegic (Mad), are downstream effectors of TGFβ/BMP signaling.
- Smad1 (Madr1 or JV4-1) and Smad5: effectors of BMP-2 and BMP-4 function
- Smad2 (Madr2 or JV18-1) and Smad3: involved in TGFβ and Activin-mediated growth modulation
- Smad4 (DPC4): mediates activities through interaction with other Smad family members
- Smad6 and Smad7: regulate Activin/TGFβ signaling by interfering with TGFβ-mediated phosphorylation of other Smad proteins
Usage Note
For Research Use Only. Not for use in diagnostic procedures.
Not for resale without express authorization.
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