
Thermo Fisher Scientific CD177 Polyclonal Antibody
Human CD177 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot에 적합. 항원 친화 크로마토그래피로 정제되어 고순도 확보. CD177 관련 염증 반응 및 세포 이동 연구에 활용 가능. 연구용으로만 사용.
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Applications
- Western Blot (WB)
Tested Dilution: 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein fragment corresponding to a region within amino acids 166–385 of Human CD177 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2547360 |
Product Specific Information
- Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji
- Predicted reactivity: Human (99%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
CD177 (NB1/HNA-2a and PRV-1 form) is a GPI-anchored glycoprotein mainly present on neutrophils. Its plasma membrane expression increases during pregnancy, inflammation, or after G-CSF application.
CD177’s ligand has been identified as CD31 (PECAM-1). It participates in neutrophil transmigration and may also function as a pro-proliferative molecule.
Antibodies against CD177 can be involved in neonatal alloimmune neutropenia (NAN).
⚠ WARNING: This product contains mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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