Thermo Fisher Scientific DUSP16 Polyclonal Antibody
Rabbit 폴리클로날 항체로 Human DUSP16 단백질을 인식하며, WB, IHC, ICC, ChIP 등 다양한 응용에 적합함. 고순도 액상 형태로 제공되며, 단기 4°C, 장기 -20°C 보관 권장. 연구용으로 MAPK 신호전달 관련 단백질 분석에 유용함.
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Thermo Fisher Scientific DUSP16 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
| ChIP assay (ChIP) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 461–665 of Human DUSP16 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.63 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2547362 |
Product Specific Information
- Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji
- Predicted reactivity: Mouse (92%), Rat (92%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Dual-specificity phosphatases (DUSPs) are a heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily.
DUSPs dephosphorylate both tyrosine and serine/threonine residues.
DUSP16, also known as MKP-7, dephosphorylates MAPK proteins ERK, JNK, and p38 with distinct specificity.
MKPs contain a conserved C-terminal catalytic domain and an N-terminal Cdc25-like domain.
MAPK activation cascades mediate processes such as cellular proliferation, apoptosis, differentiation, and stress responses.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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