Thermo Fisher Scientific USP6 Polyclonal Antibody
USP6 단백질을 인식하는 염소 유래 다클론 항체로, Western blot에 적합합니다. 0.5 mg/mL 농도의 액상 형태이며, TBS(pH 7.3)와 0.5% BSA로 보존됩니다. 인체 시료에 반응하며, 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA5142060
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1–3 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence KISPLHHLQMECSP |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2932722 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:16,000.
Target Information
USP6 is a deubiquitinase with ATP-independent isopeptidase activity, cleaving at the C-terminus of the ubiquitin moiety. It catalyzes its own deubiquitination. In vitro, isoform 2 (but not isoform 3) shows deubiquitinating activity. USP6 promotes plasma membrane localization of ARF6 and selectively regulates ARF6-dependent endocytic protein trafficking. It can initiate tumorigenesis by inducing matrix metalloproteinase production following NF-kappa-B activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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