Thermo Fisher Scientific MSRA Polyclonal Antibody
MSRA 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ICC, Flow cytometry에 적합합니다. Human 및 Mouse 시료에 반응하며, 산화 손상 방어 연구에 활용됩니다. 2 mg/mL 농도의 액상 형태로 제공되며, 4°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:10–1:50 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:10–1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide corresponding to amino acids 34–63 from the N-terminal region of human MSRA |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Ammonium sulfate precipitation, Size-exclusion, Dialysis |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2148368 |
Product Specific Information
This antibody is predicted to react with bovine based on sequence homology.
Target Information
Methionine sulfoxide reductase (MsrA) reduces methionine sulfoxide (MetO) residues in proteins and free MetO to methionine (Met). The catalytic activity of MsrA depends on bound metal and cofactors, requiring reducing equivalents from either DTT or a thioredoxin-regenerating system. MsrA plays an essential role in protecting cells against oxidative damage. Substrates of MsrA include calmodulin, HIV protease, and α1-proteinase inhibitor. Recent studies indicate a connection between MsrA and Alzheimer’s disease in mammals.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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