Thermo Fisher Scientific MSRA Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:10-1:50

-

Immunocytochemistry (ICC/IF)

1:100

-

Flow Cytometry (Flow)

1:10-1:50

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

KLH conjugated synthetic peptide between 34-63 amino acids from the N-terminal region of human MSRA if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MSRA,uniProtId:Q9UJ68-1,ncbiNodeId:9606,antigenRange:34-63,antigenLength:235,antigenImageFileName:PA5-14206_MSRA_Q9UJ68-1_Rabbit.svg,antigenImageFileNamePDP:PA5-14206_MSRA_Q9UJ68-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

2 mg/mL

Purification

Ammonium sulfate precipitation, Size-exclusion - Dialysis

Storage buffer

PBS, pH 7.4

Contains

0.09% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2148368

Product Specific Information

This antibody is predicted to react with bovine based on sequence homology.

Target Information

Methionine sulfoxide reductase (MsrA) reduces methionine sulfoxide (MetO) residues in proteins and free MetO to Methionine (Met). The catalytic activity of MsrA is dependent of bound metal and cofactors but it requires reducing equivalents from either DTT or a thioredoxin-regenerating system. MsrA plays an essential role in protecting cells against oxidative damage. The substrates of MsrA include calmodulin, HIV protease and a 1-proteinase-inhibitor. Recent studies indicate that there is a connection between MsrA and Alzheimer`s disease in mammals.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.