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Thermo Fisher Scientific BRD7 Recombinant Rabbit Monoclonal Antibody (BLR221K)
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BRD7 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot, IHC, ICC/IF, Flow cytometry, IP 등에 사용 가능. HEK293F 발현 시스템에서 제조되었으며, 고순도 정제 및 안정한 액상 형태로 제공. 연구용으로만 사용 가능.
- 판매단위
- pk
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마지막 업데이트 2025. 08. 05. 오후 09:21
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Thermo Fisher Scientific A700-221 BRD7 Recombinant Rabbit Monoclonal Antibody (BLR221K) 100 uL pk판매 단위 pk ·
재고 확인 필요
989,300원VAT 포함 1,088,230원
Thermo Fisher Scientific A700-221-T BRD7 Recombinant Rabbit Monoclonal Antibody (BLR221K) 10 uL pk판매 단위 pk ·
재고 확인 필요
263,000원VAT 포함 289,300원
Thermo Fisher Scientific · Thermo Fisher Scientific BRD7 Recombinant Rabbit Monoclonal Antibody (BLR221K)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| Flow Cytometry (Flow) | 1 µL/10⁶ cells |
| Immunoprecipitation (IP) | 12 µL/mg of lysate |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293F |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | BLR221K |
| Immunogen | Peptide representing a region between residue 601 and the C-terminus (residue 651) of Human Bromodomain-containing protein 7 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 500 µg/mL |
| Purification | Purified |
| Storage Buffer | BBS, pH 8.2, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Immunocytochemistry (ICC/IF): Epitope retrieval with citrate buffer (pH 6.0) or Tris-EDTA buffer (pH 9.0) is recommended for FFPE cell sections.
Target Information
BRD7 acts both as a coactivator and as a corepressor. It activates the Wnt signaling pathway in a DVL1-dependent manner by negatively regulating GSK3B activity. In addition, BRD7 is required for TP53-mediated cell-cycle arrest in response to oncogene activation. It promotes acetylation of TP53 at Lys-382, enhancing TP53 recruitment to target promoters and inhibiting cell cycle progression from G1 to S phase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Thermo Fisher ScientificThermo Fisher Scientific AXL Recombinant Rabbit Monoclonal Antibody (BLR222K)263,000원VAT별도
Thermo Fisher ScientificThermo Fisher Scientific BRD7 Recombinant Rabbit Monoclonal Antibody (BLR221K)1,633,500원VAT별도
Thermo Fisher ScientificThermo Fisher Scientific BRD7 Recombinant Rabbit Monoclonal Antibody (BLR220K)263,000원VAT별도
Thermo Fisher ScientificThermo Fisher Scientific BRD7 Recombinant Rabbit Monoclonal Antibody (BLR220K)1,633,500원VAT별도
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