Thermo Fisher Scientific IL-2 Monoclonal Antibody (5334), FITC
인간 IL-2에 특이적인 Mouse IgG1 단일클론 항체로 FITC 형광 표지. Flow Cytometry에 적합하며 498/517 nm에서 여기/방출. 인간 IL-2만 인식하며 다른 종 IL-2와 교차 반응 없음. 4°C 암소 보관, 액상 형태.
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Thermo Fisher Scientific IL-2 Monoclonal Antibody (Clone 5334), FITC
Applications
- Flow Cytometry (Flow)
Tested Dilution
- 10 µL / 1×10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5334 |
| Immunogen | E. coli-derived recombinant human IL-2 (Ala21–Thr153) |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Wet ice |
| RRID | AB_2608410 |
Additional Formats
Product Specific Information
This antibody does not cross-react with recombinant IL-2 from mouse, rat, pig, or cotton rat.
Target Information
Interleukin 2 (IL-2) is an immuno-modulatory cytokine important for:
- Proliferation of activated T cells
- Differentiation of B cells, NK cells, monocytes, and macrophages
IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric protein complex whose gamma chain is shared by IL-4 and IL-7.
The expression of the IL-2 gene in mature thymocytes is monoallelic, representing an unusual regulatory mode for precise gene expression.
Disruption of an IL-2-like gene in mice leads to ulcerative colitis-like disease, indicating its essential role in immune response to antigenic stimuli.
Usage Notice
For Research Use Only. Not for use in diagnostic procedures.
Not for resale without express authorization.
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